Data
The TUDA study has collected extensive data from older adults born on the island of Ireland using standardized protocols for participant sampling, assessment and data recording. Blood samples were collected, processed and laboratory analysis was centralized with remaining blood samples archived. The richness of the available data as shown below makes the TUDA cohort an invaluable resource for ageing research.
Anthropometric: Height, weight, waist circumference, hip circumference | |
Sociodemographic: Education, marital status, living arrangements | |
Lifestyle: Dietary habits, supplement use, smoking, alcohol, physical activity, sun exposure | |
Medical: Disease history, medication use, falls, family history of disease | |
Functional ability: Physical Self Maintenance Scale (PSMS), Independent Activities of Daily Living (IADL) scale, Timed Up-and-Go, Grip strength | |
Clinical measures: General haematology and clinical biochemistry profiles (lipid, liver, renal function; glycated haemoglobin), blood pressure | |
Nutritional biomarkers: Folate, vitamin B12, vitamin B6, riboflavin, vitamin D, flavanols | |
Inflammatory markers: Interleukin 6 (IL-6); interleukin 10 (IL-10); tumour necrosis factor-α (TNF-α) and C-reactive protein (CRP) | |
Neuropsychiatric health: Cognitive function using the Mini-Mental State Examination (MMSE), the Frontal Assessment Battery (FAB) and the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS); depression using the Centre for Epidemiological Studies Depression scale and anxiety using the Hospital Anxiety and Depression Scale (HADS) | |
Bone health: Bone mineral density (DXA scan), bone turnover markers | |
Genetic markers: Single nucleotide polymorphisms (SNPs); whole genome sequencing | |