A total of 5,186 community-dwelling adults, aged 60-102 years, who were born on the island of Ireland, were recruited from 2008-2012, and have been phenotypically, biochemically, genetically and clinically characterised in relation to nutrition and health. Of the cohort, 2,100 participants with a hypertension diagnosis were recruited from general practice/cardiology clinics within the Northern and Western Health and Social Care Trusts in Northern Ireland. The remaining TUDA participants were recruited from bone and memory outpatient clinics at St. James’ Hospital, Dublin.