Publications
Our publications reflect the mission of the TUDA study to better understand how food, nutrition, genetics, lifestyle, and environmental factors influence diseases of ageing – dementia, cardiovascular disease, and osteoporosis. To highlight this, we feature three key papers followed by our full list of publications to date.
2025
Angiotensin receptor blockers (ARBs) but not angiotensin converting enzyme inhibitors (ACE-Is) are associated with lower osteoclast activity and higher bone mineral density: Results from the TUDA study
Fitzpatrick, D, Laird, E, Ward, M, Hoey, L, Hughes, CF, McAnena, L, Strain, JJ, Cunningham, C, Molloy, AM, McNulty, H, Lannon, R & McCarroll, K.
Associations of one-carbon metabolism, related B-vitamins and ApoE genotype with cognitive function in older adults: identification of a novel gene-nutrient interaction
Gordon, S, Hoey, L, McNulty, H, Keenan, J, Pangilinan, F, Brody, LC, Ward, M, Strain, JJ, McAnena, L, McCann, A, Molloy, AM, Cunningham, C, McCarroll, K & Hughes, CF.
A Bagging Ensemble Machine Learning Method for Imbalanced Data to Predict Anxiety Disorders and Analysis of Risk Factors in Older People: Observational Study
Wang, J, Black, M, Rankin, D, Wallace, JG, Hughes, C, Hoey, L, Moore, AJ, Tobin, J, Zhang, M, Ng, J, Horigan, GEA, Carlin, P, McCarroll, K, Cunningham, C, McNulty, H & Molloy, A.
Co-Clustering Multi-View Data Using the Latent Block Model
Tobin, J, Black, M, Ng, J, Rankin, D, Wallace, J, Hughes, C, Hoey, L, Moore, AJ, Wang, J, Horigan, G, Carlin, P, McNulty, H, Molloy, A & Zhang, M.
Identifying comorbidity patterns of mental health disorders in community-dwelling older adults: A cluster analysis
Tobin, J, Black, M, Ng, J, Rankin, D, Wallace, JG, Hughes, C, Hoey, L, Moore, AJ, Wang, J, Horigan, G, Carlin, P, McNulty, H, Molloy, A & Zhang, M.
2024
Secondary hyperparathyroidism: Predictors and relationship with vitamin D status, bone turnover markers and bone mineral density
Fitzpatrick, D, Laird, E, Ward, M, Hoey, L, Hughes, CF, Strain, JJ, Cunningham, C, Healy, M, Molloy, AM, McNulty, H, Lannon, R & McCarroll, K.
Identification of nutrition factors in the metabolic syndrome and its progression over time in older adults: analysis of the TUDA cohort
Lyons, O, Kerr, M, Flynn, M, Hoey, L, Hughes, C, Caffrey, A, Laird, E, Moore, K, Porter, K, Cunningham, C, McCarroll, K, Molloy, AM, Tracey, F, OKane, M, Strain, JJ, Ward, M & McNulty, H.
2023
Low-Grade Systemic Inflammation is Associated with Domain-Specific Cognitive Performance and Cognitive Decline in Older Adults: Data from The TUDA Study
Dyer, AH, McNulty, H, Caffrey, A, Gordon, S, Laird, E, Hoey, L, Hughes, C, Ward, M, Strain, JJ, O’Kane, M, Tracey, F, Molloy, AM, Cunningham, C & McCarroll, K.
The association between proton pump inhibitors and hyperparathyroidism – a potential mechanism for increased fracture – results of a large observational cohort study
Fitzpatrick, D, Lannon, R, Laird, E, Ward, M, Hoey, L, Hughes, C, Strain, JJ, Cunningham, C, McNulty, H, Molloy, A & McCarroll, K.
Association of dietary flavan-3-ol intakes with plasma phenyl-γ-valerolactones: analysis from the TUDA cohort of healthy older adults
Angelino, D, Caffrey, A, McNulty, H, Gill, CI, Mena, P, Rosi, A, Moore, K, Hoey, L, Clements, M, Laird, E, Boyd, K, Mullen, B, Pucci, B, Jarrett, H, Cunningham, C, Ward, M, Strain, JJ, McCarroll, K, Moore, AJ, Molloy, AM & Del Rio, D.
Epigenetic effects of folate and related B vitamins on brain health throughout life: Scientific substantiation and translation of the evidence for health-improvement strategies
Caffrey, A, Lamers, Y, Murphy, MM, Letourneau, N, Irwin, RE, Pentieva, K, Ward, M, Tan, A, Rojas-Gomez, A, Rovira i Virgili, U, Canals, J, Leung, BMY, Bell, R, Giesbrecht, GF, Dewey, D, Field, CJ, Kobor, M, Walsh, CP & McNulty, H.
Vitamin B6 and riboflavin, their metabolic interaction and relationship with MTHFR genotype, in adults aged 18-102 years
Jarrett, H, McNulty, H, Hughes, C, Pentieva, K, Strain, JJ, McCann, A, McAnena, LB, Cunningham, C, Molloy, AM, Flynn, A, Hopkins, SM, Horigan, G, O’Connor, C, Walton, J, McNulty, B, Gibney, M, Lamers, Y & Ward, M.
2022
A 2-year randomized controlled trial with low-dose B-vitamin supplementation shows benefits on bone mineral density in adults with lower B12 status
Clements, M, Heffernan, M, Ward, M, Hoey, L, Doherty, LC, Hack Mendes, R, Clarke, MM, Hughes, CF, Love, I, Murphy, S, McDermott, E, Grehan, J, McCann, A, McAnena, LB, Strain, JJ, Brennan, L & McNulty, H.
Nutrition policy: developing scientific recommendations for food-based dietary guidelines for older adults living independently in Ireland
Lyons, OC, Flynn, MAT, Corish, CA, Gibney, ER, Kerr, MA, McKenna, MJ, McNulty, H, McSorley, EM, Nugent, AP, O’Brien, C, Ward, M, Younger, KM & Saul, I.
Reduced Kidney Function is Associated with Poorer Domain‐Specific Cognitive Performance in Community‐Dwelling Older Adults
Dyer, AH, Laird, E, Hoey, L, Hughes, CF, McNulty, H, Ward, M, Strain, JJ, O’Kane, M, Tracey, F, Molloy, AM, Cunningham, C, Sexton, DJ & McCarroll, K.
2021
Associations of atrophic gastritis and proton-pump inhibitor drug use with vitamin B12 status, and the impact of fortified foods, in older adults
Porter, K, Hoey, L, Hughes, C, Ward, M, Clements, M, Strain, JJ, Cunningham, C, Casey, M, Tracey, F, O’Kane, M, Pentieva, K, McAnena, LB, McCarroll, K, Laird, E, Molloy, AM & McNulty, H.
Long‐term anticholinergic, benzodiazepine and Z‐drug use in community‐dwelling older adults: What is the impact on cognitive and neuropsychological performance?
Dyer, AH, Laird, E, Hoey, L, Hughes, CF, McNulty, H, Ward, M, Strain, JJ, Molloy, AM, Cunningham, C & McCarroll, K.
Glycated Haemoglobin (HbA1c), Diabetes and Neuropsychological Performance in Community-Dwelling Older Adults
Dyer, AH, Briggs, R, Laird, E, Hoey, L, Hughes, C, McNulty, H, Ward, M, Strain, JJ, Molloy, AM, Cunningham, C & McCarroll, K.
Vitamin D and Hospital Admission in Older Adults: A Prospective Association
Beirne, A, McCarroll, K, Walsh, JB, Casey, M, Laird, E, McNulty, H, Ward, M, Hoey, L, Molloy, AM, Healy, M, Hughes, C, Strain, JJ & Cunningham, C.
2020
Impact of the common MTHFR 677C→T polymorphism on blood pressure in adulthood and role of riboflavin in modifying the genetic risk of hypertension: evidence from the JINGO project
Ward, M, Hughes, C, Strain, JJ, Reilly, R, Cunningham, C, Molloy, A, Horigan, G, Casey, M, McCarroll, K, O’Kane, M, Gibney, M, Flynn, A, Walton, J, McNulty, B, McCann, A, Kirwan, L, Scott, J & McNulty, H.
Why dietary polyphenols are important for the ageing brain: Early findings from the VALID project
Caffrey, A, Gill, CIR, Del Rio, D, Angelino, D, Molloy, AM, Cunningham, C, Moore, AJ, Ward, M & McNulty, H.
Identifying Key Predictors of Cognitive Dysfunction in Older People Using Supervised Machine Learning Techniques: Observational Study
Rankin, D, Black, M, Flanagan, B, Hughes, C, Moore, A, Hoey, L, Wallace, J, Gill, C, Carlin, P, Molloy, A, Cunningham, C & McNulty, H.
2019
Hyperglycemia and Metformin Use Are Associated With B Vitamin Deficiency and Cognitive Dysfunction in Older Adults
Porter, KM, Ward, M, Hughes, CF, O’Kane, M, Hoey, L, McCann, A, Molloy, AM, Cunningham, C, Casey, MC, Tracey, F, Strain, S, McCarroll, K, Laird, E, Gallagher, AM & McNulty, H.
B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study
Moore, K, Hughes, C, Hoey, L, Ward, M, Cunningham, C, Molloy, AM, Strain, JJ, McCarroll, K, Casey, M, Tracey, F, Laird, E, O’Kane, M & McNulty, H.
2018
Effect of Area-Level Socioeconomic Deprivation on Risk of Cognitive Dysfunction in Older Adults
McCann, A, McNulty, H, Rigby, J, Hughes, CF, Hoey, L, Molloy, AM, Cunningham, CJ, Casey, MC, Tracey, F, O’Kane, MJ, McCarroll, K, Ward, M, Moore, K, Strain, JJ & Moore, A.
The relationship between adiposity and cognitive function in a large community-dwelling population: data from the Trinity Ulster Department of Agriculture (TUDA) ageing cohort study
Ntlholang, O, McCarroll, K, Laird, E, Molloy, AM, Ward, M, McNulty, H, Hoey, L, Hughes, C, Strain, JJ, Casey, M & Cunningham, C.
2017
Greater yogurt consumption is associated with increased bone mineral density and physical function in older adults
Laird, E, Molloy, AM, McNulty, H, Ward, M, McCarroll, K, Hoey, L, Hughes, C, Cunningham, C, Strain, JJ & Casey, MC.
Ambient UVB Dose and Sun Enjoyment Are Important Predictors of Vitamin D Status in an Older Population
O’Sullivan, F, Laird, E, Kelly, D, van Geffen, J, van Weele, M, McNulty, H, Hoey, L, Healy, M, McCarroll, K, Cunningham, C, Casey, M, Ward, M
2016
Dairy intakes in older Irish adults and effects on vitamin micronutrient status: Data from the TUDA study
Laird, E, Casey, MC, Ward, M, Hoey, L, Hughes, C, Mccarroll, K, Cunningham, C, Strain, JJ, McNulty, H & Molloy, AM.
The Frontal Assessment Battery: Normative Performance in a Large Sample of Older Community-Dwelling Hospital Outpatient or General Practitioner Attenders
Coen, RF, McCarroll, K, Casey, M, McNulty, H, Laird, E, Molloy, AM, Ward, M, Strain, S, Hoey, L, Hughes, C & Cunningham, CJ.
2015
Determinants of 25-hydroxyvitamin D in older Irish adults
McCarroll, K, Beirne, A, Casey, M, McNulty, H, Ward, M, Hoey, L, Molloy, A, Laird, E, Healy, M, Strain, JJ & Cunningham, C.
2014
Vitamin D Deficiency Is Associated With Inflammation in Older Irish Adults
Laird, E, McNulty, H, Ward, M, Hoey, L, McSorley, EM, Wallace, JMW, Carson, E, Molloy, AM, Healy, M, Casey, MC, Cunningham, C & Strain, JJ.
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